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Organoboron Chemistry
Novel organoboron compounds and building blocks, at high chemical and optical purity with a short cycle time.
The platform
- Rich experience in C–H borylation, with better than 98% success ratio for scale-up
- A wide substrate scope, at synthetic scales from milligrams to hundreds of grams
- Boronic acids, amino boronic acids, tertiary boronic esters, cyclic boronic esters and MIDA boronates
- A high success rate in developing novel organoboron compounds
- Quick turnaround, with most organoboron synthesis run by chemists with extensive boron chemistry experience
Why the class needs a standing team
Organoboron intermediates are the workhorse of cross-coupling, and the ones a program actually needs are rarely the ones a catalogue holds. Making them at useful purity and useful scale, repeatably, is what the platform is for.